Prostate cancer incidence continues to rise by about 1% per year in the United States, with 192,000 new cases diagnosed in 2009. As increasing numbers of men follow recommendations to undergo PSA testing and digital rectal examination, the chances of detecting cancer still confined to the prostate—with optimal chances for a cure—also increase. How can clinicians help each patient make the best decisions regarding screening, biopsy, and (when required) treatment for the cancer that is second most common among US men?
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