Unexpected findings from the Women’s Health Initiative led many clinicians to think twice before prescribing hormone or estrogen replacement therapy (HRT, ERT) for women with troublesome, even severe, symptoms of menopause. Did researchers make overly broad generalizations about the risks of HRT/ERT use? How can the potential benefits of HRT/ERT be effectively balanced with each patient’s risk factors for breast cancer, heart disease, osteoporotic fractures, postmenopausal dementia—and her quality of life?
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