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As with US adults, infants and children appear to be at increased risk for gastroesophageal reflux disease (GERD). Lacking a cardinal symptom in children and often linked with confounding extra-esophageal symptoms, pediatric GERD...
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Heparin-induced thrombocytopenia is an immune-mediated drug reaction to anticoagulant therapy that requires prompt detection and treatment to minimize morbidity and mortality. ...
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HIT should be suspected in any patient whose history shows heparin use within the previous two weeks (even if the drug has been discontinued). ...
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The diagnosis of HIT is determined by combining clinical and serologic assessments. The 4Ts scoring strategy to determine the patient’s probability of HIT is included here. ...
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The goal in management of HIT—to reduce the likelihood, then the severity, of thrombosis—is achieved by discontinuing all heparin exposure and substituting a non-heparin anticoagulant. Dosing guidelines for direct thrombin inhibitors are...
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This is the complete reference list for this multi-part article. ...
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Patients—and many health care providers—may not be prepared to handle the results of genetic testing. ...
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Genetic testing has grown exponentially since 1993: There are now tests for 2,978 diseases. ...
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Many health care providers find genetic testing to be unfathomable; imagine how patients feel. ...
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The results of genetic testing can't always be put to practical use--or the available treatment options may be extreme. ...
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Armed with new "technology," health care providers may be losing sight of the fundamentals of patient care--some of which yield valuable clues to a patient's future. ...
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A reader requests additional information about cognitive screening tools: the most comprehensive screening instrument, and ways to score the clock drawing test, including its effectiveness in assessing driver safety. ...
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Teens should be warned about the dangers of using weight-loss products that contain wild ginger. ...
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Should a diabetic patient with proteinuria who does not respond to treatment with an ACE inhibitor have an angiotensin receptor blocker added to her regimen? ...
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During a “routine” surgery, hypertension resulting from an anesthetic drug is overtreated, leading to hypoxic brain injury. ...
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An apparent foot sprain is recognized too late as a virulent group A streptococcal infection. ...
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In response to our March cover story, a reader shares a harrowing story of finding out, firsthand, just how poorly the mentally ill can be treated by individuals in the health care system. ...
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In response to our March cover story, a reader argues that the United States needs to stop "overprotecting" mentally ill patients' right to refuse medication and treatment. ...
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