Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Prevention of CVD in Adults with Type 2 Diabetes
AHA/ADA provides updated scientific statement
The American Heart Association (AHA) and the American Diabetes Association (ADA) issued a scientific statement updating recommendations for cardiovascular disease prevention in adults with type 2 diabetes mellitus. Recommendations include:
• Lifestyle modification, including increased physical activity through increased daily physical activity and aerobic exercise
• Nutrition education – DASH, Mediterranean, low-fat, or monitored carbohydrate diets
• Control of Obesity – Caloric restriction and behavioral counseling to comply with dietary recommendations. Pharmacologic and surgical approaches may be considered for patients who do not respond to lifestyle interventions.
• Glucose Control – A1c <7.0% for most patients, with goal individualized based on patients duration of diabetes and comorbidities.
• Avoidance of hypoglycemia
• Aspirin – Low-dose aspirin (75-162 mg daily) is “reasonable” if 10-year risk of coronary disease is greater than 5%, with the evidence being stronger for risk >10%.
• Blood Pressure – Goal < 140/90
• Cholesterol - Patients aged 40 to 75 years with LDL between 70 and 189 mg/dL should be treated with a moderate-intensity statin, and a high-intensity statin should be used if estimated 10-year risk of coronary disease is > 7.5%.
Citation: Fox CS, Golden SH, Anderson C, et al. Update on prevention of cardiovascular disease in adults with type 2 diabetes mellitus in light of recent evidence. Circulation. [Published online ahead of print August 5, 2015]. doi: 10.1161/CIR.0000000000000230.
1. American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Executive summary: heart disease and stroke statistics—2013 update: a report from the American Heart Association. Circulation. 2013;127:143–152. doi: 10.1161/CIR.0b013e318282ab8f.
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